Location: SLC transporters @ 27b936ef317a / Electrogenic cotransporter / CellMLV2 / params_ss_fast.cellml

Author:
Weiwei Ai <wai484@aucklanduni.ac.nz>
Date:
2024-05-27 15:58:59+12:00
Desc:
Test the path setting in readme
Permanent Source URI:
https://models.physiomeproject.org/workspace/b65/rawfile/27b936ef317a4bbffdfb731a8adc084c7fdb1d5b/Electrogenic cotransporter/CellMLV2/params_ss_fast.cellml

<?xml version="1.0" encoding="UTF-8"?>
<model xmlns="http://www.cellml.org/cellml/2.0#" name="params_BG">
  <import xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="./units.cellml">
    <units units_ref="per_fmol" name="per_fmol"/>
    <units units_ref="C_per_mol" name="C_per_mol"/>
    <units units_ref="fmol_per_s" name="fmol_per_s"/>
    <units units_ref="fmol" name="fmol"/>
    <units units_ref="J_per_K_mol" name="J_per_K_mol"/>
    <units units_ref="mM" name="mM"/>
    <units units_ref="pL" name="pL"/>
    <units units_ref="fA" name="fA"/>
    <units units_ref="fF" name="fF"/>
  </import>
  <component name="params_BG">
    <variable name="R" units="J_per_K_mol" initial_value="8.31" interface="public"/>
    <variable name="T" units="kelvin" initial_value="293" interface="public"/>
    <variable name="F" units="C_per_mol" initial_value="96485" interface="public"/>
    <variable name="K_Nai" units="per_fmol" initial_value="1.413e-07" interface="public"/>
    <variable name="q_Nai" units="fmol" interface="public"/>
    <variable name="K_Nao" units="per_fmol" initial_value="1.413e-07" interface="public"/>
    <variable name="q_Nao" units="fmol" interface="public"/>
    <variable name="K_Glci" units="per_fmol" initial_value="5.715e-06" interface="public"/>
    <variable name="q_Glci" units="fmol" interface="public"/>
    <variable name="K_Glco" units="per_fmol" initial_value="5.715e-06" interface="public"/>
    <variable name="q_Glco" units="fmol" interface="public"/>
    <variable name="K_1" units="per_fmol" initial_value="3.660" interface="public"/>
    <variable name="q_init_1" units="fmol" initial_value="16.605778811026234" interface="public"/>
    <variable name="K_2" units="per_fmol" initial_value="3.301e+02" interface="public"/>
    <variable name="q_init_2" units="fmol" initial_value="16.605778811026234" interface="public"/>
    <variable name="K_3" units="per_fmol" initial_value="3.207e+02" interface="public"/>
    <variable name="q_init_3" units="fmol" initial_value="16.605778811026234" interface="public"/>
    <variable name="K_4" units="per_fmol" initial_value="3.207e+02" interface="public"/>
    <variable name="q_init_4" units="fmol" initial_value="16.605778811026234" interface="public"/>
    <variable name="K_5" units="per_fmol" initial_value="9.053e+02" interface="public"/>
    <variable name="q_init_5" units="fmol" initial_value="16.605778811026234" interface="public"/>
    <variable name="K_6" units="per_fmol" initial_value="0.314" interface="public"/>
    <variable name="q_init_6" units="fmol" initial_value="16.605778811026234" interface="public"/>
    <variable name="V0_Vm" units="volt" initial_value="-0.15" interface="public"/>
    <variable name="z_zf1" units="dimensionless" initial_value="0.3" interface="public"/>
    <variable name="z_zf6" units="dimensionless" initial_value="0.7" interface="public"/>
    <variable name="kappa_r1" units="fmol_per_s" initial_value="1.515e+04" interface="public"/>
    <variable name="kappa_r2" units="fmol_per_s" initial_value="6.237e+02" interface="public"/>
    <variable name="kappa_r3" units="fmol_per_s" initial_value="0.156" interface="public"/>
    <variable name="kappa_r4" units="fmol_per_s" initial_value="2.495e+04" interface="public"/>
    <variable name="kappa_r5" units="fmol_per_s" initial_value="1.105e+02" interface="public"/>
    <variable name="kappa_r6" units="fmol_per_s" initial_value="9.562" interface="public"/>
    <variable name="kappa_r7" units="fmol_per_s" initial_value="9.089e-04" interface="public"/>
    <variable name="Nai" units="mM" initial_value="20"/>
    <variable name="Nao" units="mM" initial_value="100"/>
    <variable name="Glci" units="mM" initial_value="10e-3"/>
    <variable name="Glco" units="mM" initial_value="1e-12"/>
    <variable name="V_i" units="pL" initial_value="8.5e5"/>
    <variable name="V_o" units="pL" initial_value="8.5e5"/>
    <variable name="t" units="second" interface="public"/>
    <math xmlns="http://www.w3.org/1998/Math/MathML" xmlns:cellml="http://www.cellml.org/cellml/2.0#">
      <apply>
        <eq/>
        <apply>
          <diff/>
          <bvar>
            <ci>t</ci>
          </bvar>
          <ci>V0_Vm</ci>
        </apply>
        <apply>
          <divide/>
          <cn cellml:units="volt">0.01</cn>
          <cn cellml:units="second">1</cn>
        </apply>
      </apply>
      <apply>
        <eq/>
        <ci>q_Nai</ci>
        <apply>
          <times/>
          <ci>Nai</ci>
          <ci>V_i</ci>
        </apply>
      </apply>
      <apply>
        <eq/>
        <ci>q_Nao</ci>
        <apply>
          <times/>
          <ci>Nao</ci>
          <ci>V_o</ci>
        </apply>
      </apply>
      <apply>
        <eq/>
        <ci>q_Glci</ci>
        <apply>
          <times/>
          <ci>Glci</ci>
          <ci>V_i</ci>
        </apply>
      </apply>
      <apply>
        <eq/>
        <ci>q_Glco</ci>
        <apply>
          <times/>
          <ci>Glco</ci>
          <ci>V_o</ci>
        </apply>
      </apply>
    </math>
  </component>
</model>